What are Singer and Nicolson known for?
a. One gene one enzyme hypothesis
b. Plasma membrane modification
c. Fluid mosaic model of plasma membrane
d. Structure of DNA

Hint: The cell membrane describes two dimensional liquid that binds with the lateral diffusion of membrane components. In the membrane some kind of special lipids, proteins cocoon are present that promote the formation of protein, glycoprotein and lipid rafts. And on the other side cytoskeleton filaments and extracellular matrix bind with the membrane domain through the membrane proteins.

Complete answer:
The fluid mosaic model which was discovered by SJ Singer and G.L Nicolson bin 1972. The model now used for the important features in the biological sciences as cellular processes, apoptosis, cell division and cell cell signaling. Fluid mosaic model is the most useful model in the plasma membrane because it helps to separate the contents of the cell from the outside.

Chemically cell membrane composed of four type components
a) Phospholipids
b) Proteins
c) Carbohydrates
d) Cholesterol.

The fluid present in the membrane has been determined with the help of x-ray diffraction and calorimetry. This model provides some important modification to the fluid and dynamic biological model that was performed by Frye and Edidin. Fluid mosaic models help to explain the cell membrane behavior and structure under the different temperature and protein levels present inside the membrane.

Hence, the correct answer is option (C).

Note: Fluorescence microscopy and structural biology support the model have validated fluid mosaic nature of the cell membrane present in it. The plasma membrane that is present in the cell membrane represents a sandwich-like structure filled with proteins, cholesterol and phospholipids. It looks like a fluid structure because protein molecules are embedded between the two layers of the membrane walls.